IDP/Thesis: Physics-based deep learning for hyperspectral brain surgery imaging

Hyperspectral imaging (HSI) is an optical technique that processes the electromagnetic spectrum at a multitude of monochromatic, adjacent frequency bands. The wide-bandwidth spectral signature of a target object’s reflectance allows fingerprinting its physical, biochemical, and physiological properties. HSI has been applied for various applications, such as remote sensing and biological tissue analysis. Recently, HSI was also used to differentiate between healthy and pathological tissue under operative conditions in a surgery room on patients diagnosed with brain tumors [1].

Within the HyperProbe project, we aim to develop a novel all-optical, AI-powered intraoperative imaging system to transform monitoring of brain tumour surgery. Your goal would be to develop a methodology at the intersection between physics and machine-learning to identify biomarkers of healthy and tumor brain tissue.


Your qualifications:

  • Enthusiasm for merging physics with AI for developing new biomedical imaging modality
  • Ideally, prior work experience using deep learning for image processing
  • Decent programming skills in Python as well as PyTorch or Tensorflow

What we offer:

  • An exciting research project aimed to build a new imaging modality that has a potential to change the neurosurgery monitoring in the near future
  • Close supervision and access to state-of-the-art computer hardware
  • The chance to work in a team of experts in image processing, deep learning, biomedical engineering and medicine

How to apply:

Send an email to with your CV and transcript.


[1] Luca Giannoni, Frédéric Lange and Ilias Tachtsidis. Hyperspectral imaging solutions for brain tissue metabolic and hemodynamic monitoring: past, current and future developments, J. Opt. 20 (2018)

Ivan Ezhov
Ivan Ezhov
Research Scientist

My research focuses on physics-based machine learning for biomedical applications.